Fluorescence helps in ulcer treatment
22 Mar 2005 by Evoluted New Media
Russian researchers have developed a novel approach to the treatment of gastrointestinal ulcers. They have discovered that not only does the ulcer hurt, it fluoresces, which may help when deciding the correct treatment option.
Russian researchers have developed a novel approach to the treatment of gastrointestinal ulcers. They have discovered that not only does the ulcer hurt, it fluoresces, which may help when deciding the correct treatment option.
The specialists from the Moscow Regional Scientific-Research Clinical Institute (MONIKI) have developed a fibre optic spectrum analyser that can measure the intensity of fluorescence from the surface of the gastrointestinal tract. Determining the fluorescence intensity will allow doctors to determine how successful a course of laser therapy would be and help select optimal irradiation conditions.
Low intensity laser irradiation was introduced about 40 years ago as a therapy for inflammatory diseases. Multiple diseases are accompanied by an increase of porphyrins, complex organic molecules found in the cells. These molecules are extremely sensitive to the red component of the spectrum, therefore tissues with a high porphyrin content become likely targets for laser irradiation.
Laser irradiation accelerates wound healing by activating the defence functions and division processes of the cells. Fluorescence intensity depends on the quantity of porphyrins found in the tissues, and enables doctors to adjust the level of irradiation accordingly. As the ulcer heals the fluorescence intensity weakens, signifying healing the end of treatment.
Further information Sergey Komarov, Informanuka (Information) Agency
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